A Comparitive Study of Serum Pro-Calcitonin (S- Pct) & C-Reactive Protein ( CRP) in Patients with Sepsis.

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Shraddha Toutem
Virendra C. Patil


Background: Studies have shown that, early diagnosis & treatment of sepsis can lower the mortality rates & improved their related outcomes.Furthermore, studies revealed that, S-PCT can used as biomarker for early diagnosis & guiding therapeutic decision for treatment of sepsis. Thus, in our  study our  aim was to evaluate & compare the utility of S-PCT & CRP as diagnostic markers , calculate SOFA score and finally, relate these biomarkers with SOFA score .

Material And Methods: Our study was a single center hospital-based, prospective, observational and non- interventional type of study with total of 58 patients with sepsis.

Results: Out of 58 patients in total, 31 (53.4 %) were males & 27 (46.6%) were females. The mean S-PCT and mean CRP measured as markers of sepsis showed 17.97 (±21.78) ng/mL & 46.81 (±34.21) mg/L respectively. The mean SOFA score of the patients was 8.51 (±3.34). Mean S-PCT levels were higher in patients with a higher SOFA score which was statistically significant.

Conclusion: In our present study we have concluded that, both S-PCT & CRP levels were consistent markers for systemic infection.

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How to Cite
Shraddha Toutem, & Virendra C. Patil. (2023). A Comparitive Study of Serum Pro-Calcitonin (S- Pct) & C-Reactive Protein ( CRP) in Patients with Sepsis. Journal of Coastal Life Medicine, 11(2), 718–727. Retrieved from https://www.jclmm.com/index.php/journal/article/view/1080


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