A Comparitive Study of Serum Pro-Calcitonin (S- Pct) & C-Reactive Protein ( CRP) in Patients with Sepsis.
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Abstract
Background: Studies have shown that, early diagnosis & treatment of sepsis can lower the mortality rates & improved their related outcomes.Furthermore, studies revealed that, S-PCT can used as biomarker for early diagnosis & guiding therapeutic decision for treatment of sepsis. Thus, in our study our aim was to evaluate & compare the utility of S-PCT & CRP as diagnostic markers , calculate SOFA score and finally, relate these biomarkers with SOFA score .
Material And Methods: Our study was a single center hospital-based, prospective, observational and non- interventional type of study with total of 58 patients with sepsis.
Results: Out of 58 patients in total, 31 (53.4 %) were males & 27 (46.6%) were females. The mean S-PCT and mean CRP measured as markers of sepsis showed 17.97 (±21.78) ng/mL & 46.81 (±34.21) mg/L respectively. The mean SOFA score of the patients was 8.51 (±3.34). Mean S-PCT levels were higher in patients with a higher SOFA score which was statistically significant.
Conclusion: In our present study we have concluded that, both S-PCT & CRP levels were consistent markers for systemic infection.
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References
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