Formulation and Evaluation of Delayed Release Fenofibric Acid Capsule
Main Article Content
Abstract
The active pharmaceutical ingredient Choline fenofibate was subjected to preformulation study, which encompasses the “Accelerated, intermediate, long term Drug – excipient compatibility study” , and the result obtained with selected excipients showed good compatibility with Choline fenofibrate.Choline fenofibrate pellets were formulated by utilization of FBP, and Choline fenofibrate coated pellets were filled by capsule filling machine.
The stability study of the capsule and pellets were detected by conducting “accelerated 40°C±5%/75%RH” for 6 months. Finally, after the duration, the product was analyzed for content and dissolution study. By the stability studies, the formulated Fenofibric acid Delayed release capsules and pellets proved to be throughout the period of storage.TheFenofibric acid delayed release pellets were loaded in size ‘0’ capsules. It showed good results in formulation of stable dosage.
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References
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