Ormeloxifene an Effective Alternative for Surgery for Abnormal Uterine Bleeding of Ovulatory Disorders.

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Priyanka Karumuri
Shailaja R Bidri
Sangamesh Mathapati


Introduction: Abnormal uterine bleeding is a significant debilitating clinical condition and effect 14-25% of women. We sought to determine the effectiveness and potency of Ormeloxifene in the treatment of AUB-O in this longitudinal investigation.

Objectives: To study the efficacy and acceptability of Ormeloxifene in management of AUB.

Methodology: The study was conducted in Department of Obstetrics and Gynecology of BLDE(DU) Shri B M Patil medical college. In this study 52 patients aged 30-55 years, presenting with heavy menstrual bleeding were enrolled. Patients with any structural pelvic cause, liver dysfunctions, who are using IUCDs or oral contraceptives, were excluded from the study. All the participants were subjected for complete menstrual history, medical history, clinical examination and laboratory evaluation done. All cases received Ormeloxifene 60mg twice weekly for the first 12 weeks, followed by once weekly for next 12 weeks. The participants were followed every three months and six months for subjective and objective improvement in menstrual blood loss by history, measuring PBAC score, endometrial thickness, hemoglobin concentration.

Results: 50 out of 52 study participants completed the treatment and all 50 had improvement in symptoms of HMBL after using Ormeloxifene for 6 months. They had minimal and minor side effects. There was improvement in hemoglobin concentration, PBAC score, TVS-ET score in all the participants.

Conclusion: Ormeloxifene is effective and safe in patients with AUB-O and this can reduce the burden of surgery in patients suffering from AUB-O.

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How to Cite
Priyanka Karumuri, Shailaja R Bidri, & Sangamesh Mathapati. (2023). Ormeloxifene an Effective Alternative for Surgery for Abnormal Uterine Bleeding of Ovulatory Disorders. Journal of Coastal Life Medicine, 11(2), 944–949. Retrieved from https://www.jclmm.com/index.php/journal/article/view/1111


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