Microneedle-Based Transdermal Drug Delivery: A Comprehensive Overview
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Abstract
Microneedle-based drug delivery systems offer a convenient alternative to traditional hypodermic injections, addressing concerns related to patient acceptance and injection safety. Unlike conventional transdermal methods, which rely on drug diffusion through the skin barrier, microneedles enable the delivery of macromolecular drugs like insulins and vaccines by creating microscale pathways into the body. These tiny needles penetrate only the outer layers of the skin, avoiding contact with nerve receptors in the deeper skin, resulting in painless insertions. This comprehensive review provides an overview of microneedle technology, discussing its advantages, disadvantages, various types, and applications in drug delivery.
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References
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