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The COVID-19 pandemic caused by SARS-CoV-2 has raised concerns about its impact on the nervous and immune systems, particularly in adolescents. This study aimed to assess the interdependence between neuroimmunological markers and neurological status in adolescents during the post-COVID period.
A comprehensive literature review was conducted to gather relevant information on the topic. The available evidence suggests that COVID-19 can lead to neurological symptoms during the acute phase of the infection, ranging from mild to severe manifestations. Additionally, the dysregulation of immune responses, including the release of pro-inflammatory cytokines and chemokines, has been observed in COVID-19 patients. To assess the interdependence between neuroimmunological markers and neurological status, various research approaches are utilized. These include measuring levels of inflammatory markers, such as C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-alpha), and correlating them with neurological symptoms. Longitudinal studies involving large sample sizes are crucial to understanding the evolution of these markers and neurological status over time. Overall, this assessment highlights the need for further research to elucidate the long-term effects of COVID-19 on neurological health in adolescents. The findings will assist healthcare providers in developing targeted interventions and management strategies for individuals experiencing persistent neurological symptoms in the post-COVID period.
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