Evaluation of Anti-Dandruff Activity of Polyherbal Serum Against the Fungus Malasseiza Fungus from Human Scalp

Main Article Content

B. Mohanapriya
S.N. Suresh
A. Sathyapriya
C. Kanagaraj
N. Mythily


Dandruff is one of the most common problems faced by people all around the world. It is a dermatological disorder that can be extremely frustrating and embarrassing. Fortunately, a recent study has shown promising results in the fight against dandruff. The study aimed to investigate the effectiveness of a polyherbal formulation against Malassezia furfur, a fungus that is often responsible for causing dandruff. The polyherbal formulation used in the study was composed of various leaves, including Piper betal, Tictona grandis, and Eclipta prostrata, as well as flowers such as Tenner cassia. Diffusion-dependent assays were used to determine the mixture's anti-malassezial activity after it had been extracted with both water (APHF) and methanol (MPHF).The results of the study were very encouraging. Both MPHF and APHF, which underwent GC-MS analysis and qualitative testing for various kinds of phytochemicals, showed the existence of numerous active metabolites that may inhibit M. furfur and have potential for use as anti-dandruff treatments.

Article Details

How to Cite
B. Mohanapriya, S.N. Suresh, A. Sathyapriya, C. Kanagaraj, & N. Mythily. (2023). Evaluation of Anti-Dandruff Activity of Polyherbal Serum Against the Fungus Malasseiza Fungus from Human Scalp. Journal of Coastal Life Medicine, 11(2), 1443–1447. Retrieved from https://www.jclmm.com/index.php/journal/article/view/1178


Kumar, P. S., Sucheta, S., Deepa, V. S., Selvamani, P., & Latha, S. (2008). Evaluation of antidandruff activity using polyherbal oil from six medicinal plants. Journal of Biotechnology, (136), S408-S409.


Rakkimuthu, R., Nithiyakamatchi, R., Sathishkumar, P., Ananda Kumar, A. M., & Sowmiya, D. (2019). In vitro antifungal activity of formulated floral extracts against Malassezia furfur. Int. J. Anal. Exp. Modal Anal, 6, 1-10.

Manjula B, Sundara Raja Rao V, Vijayalakshmi P. In vitro anti-Malassezia activity of Piper betle and Swiss chard leaf extracts. Journal of Pharmacy Research. 2013;6(8):828-831.

Kumar S, Santra S, Bhattacharya SK, Banerjee PK. Anti-dandruff activity of Cassia alata leaf extract against Malassezia furfur. Asian Pacific Journal of Tropical Medicine. 2011;4(11):876-879.

Sankar S, Palanisamy S, Shanthi G, et al. Antimicrobial activity of Tectona grandis Linn leaves extract against Malassezia furfur – A causative agent of dandruff. International Journal of Pharmaceutical Research and Development. 2011;3(7):57-61.

Ghosh N, Mandal A, Roy S. Evaluation of anti-dandruff activity of aqueous extract of Eclipta prostrata in vitro. Asian Journal of Pharmaceutical and Clinical Research. 2013;6(2):197-199.

Muthukrishnan S, Nagarajan S, Nagalingam M, Velusamy P. Evaluation of in vitro anti-dandruff activity of Tectona grandis Linn. leaves extract. International Journal of Advanced Research in Biological Sciences. 2015;2(5):159-166.

Kamal MA, Hossain MS, Islam MA, et al. Phytochemical and biological studies on Cassia tora Linn. International Journal of Pharmaceutical Sciences and Research. 2012;3(10):3883-3891.

Jain N, Sharma N, Lodha M, Sharma PK. Anti-dandruff activity of different plant extracts: An in vitro study. International Journal of Green Pharmacy. 2013;7(3):212-216.

Saha S, Basak S, Ghosh S. Anti-dandruff activity of herbal extracts. Journal of Analytical Science and Technology. 2014;5(1):9.

Jaiswal R, Bhatia E, Maurya AK, et al. Antifungal activity of Cassia fistula extract against Malassezia furfur: An in vitro study. Asian Journal of Pharmaceutical and Clinical Research. 2011;4(4):99-101.

Kishore N, Mishra BB, Tiwari VK. Antifungal activity of Eclipta prostrata (L) L against Malassezia furfur. Indian Journal of Traditional Knowledge. 2010;9(3):508-511.

Kumar S, Ramesh C, Santra S, Bhattacharya SK, Banerjee PK. Antifungal activity of Cassia alata leaf extract against Malassezia furfur (ATCC 14521) in vitro. Bulletin of Faculty of Pharmacy, Cairo University. 2014;52(1):1-5.

Joydeep N, Saha MR, Saha B, et al. In vitro screening of some indigenous medicinal plants for their anti-dandruff activity. J Life Sci. 2011;3:77-83.

Fatima S, Haider S, Rizvi TA, et al. In vitro anti-Malassezia furfur activity of different concentrations of Tectona grandis Linn. leaves extracts. Indian Journal of Fundamental and Applied Life Sciences. 2015;5(S1):1-5.

Park YK, Kim YO. Antimicrobial activity of ethanol and water extracts from medicinal plants against Malassezia furfur. Yeungnam University Journal of Medicine. 2002;19(2):193-199.

Gomathi S, Anuradha V, Lakshmi BV, et al. In vitro antifungal activity of selected plant extracts against Malassezia furfur. Research Journal of Pharmacy and Technology. 2011;4(7):1101-1104.

Philomina PT, Sharma N. In vitro evaluation of anti-Malassezia furfur activity of herbal extracts. International Journal of Herbals and Pharmacognosy. 2014;3(4):110-114.

Dhama K, Tiwari R, Chakraborty S, et al. Herbal antifungal agents: Current status and future perspectives. Expert Opinion on Biological Therapy. 2012;12(7):861-882.

Thakur R, Jain N, Pathak R, et al. Anti-dandruff activity and formulation of herbal hair oil from the leaves of Azadirachta indica A. Juss. and Eclipta prostrata L. Journal of Medicinal Plants Research. 2013; 7(6):257-264.

Savitri, Rai SK. Antifungal activity of certain plant extracts against dandruff causing Malassezia furfur – An in vitro study. Journal of Chemical and Pharmaceutical Research. 2014;6(11):35-39.

Murali P, Naidu M, Sivakumar R. In vitro antifungal activity of some plant extracts against Malassezia furfur. World Journal of Pharmaceutical Sciences. 2014;3(3):457-462

Saunders CW, Scheynius A, Heitman J. PLoS Pathog., 2012; 8(6): p.e1002701