Impact of Polyunsaturated Fatty Acids on Body Mass Index-ACorrelation Study in Type 2 Diabetic Postmenopausal Women
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Abstract
Background: The relationship of n-3 and n-6 fatty acid in diabetic postmenopausal women remains unclear and the association of theses fatty acids with obesity is debated. The pattern of PUFA among diabetic and non-diabetic women helped to clarify the correlation. The study aimed to determine the pattern of Poly unsaturated fatty acids among the diabetic case and control women and to correlate the PUFA with body mass index (BMI).
Materials and Method
Plasma PUFA was measured by gas chromatography among 120 type 2 diabetes mellitus post-menopausal women and 120 non diabetic postmenopausal women. Fasting blood samples were collected among the postmenopausal women.
Results and Discussion
Noticeable differences between the plasma phospholipid compositions among the groups were observed. Lower percentage of n-3 fatty acid was observed in diabetic postmenopausal women when compared with controls. Spearman's correlation showed an inverse relationship of EPA and DPA showed with BMI among the case group which was statistically significant (p<0.012; p<0.025).
Interpretation and conclusion
Lower EPA and DHA levels promotes obesity and metabolic abnormalities related to obesity.
Article Details
References
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