Seroprevalence of Transfusion-Transmissible Infectious Agents (HIV, HBV, HCV, Syphilis, and Malaria) in Voluntary Blood Donors in a Tertiary Care Center in Ghaziabad (U.P.)

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Swati Singh
Mayurika Tyagi


Background: Voluntary blood donation is undoubtedly, the highest form of humanitarian service as it is done without expectation of even knowing who it will help. One single blood donation actually helps many patients as blood is usually segregated into red blood cells (RBCs), Platelets, white blood cells (WBCs) and Plasma and given accordingly for their requirement.

Aim and Objective: Seroprevalence of transfusion-transmissible infectious agent (HIV, HBV, HCV, syphilis, and malaria) among voluntary blood donors in a tertiary care facility in Ghaziabad (U.P.)

Methodology: The current study was carried out from June 2018 to May 2020 at the blood bank connected to Santosh Medical College & Hospital, in Ghaziabad, Uttar Pradesh. Clear serum was prepared by centrifuging blood taken from the collection bag's tubing into a labelled tube. The samples were then tested for Syphilis, Malaria, HIV, HBV, and HCV as these all are blood borne infections that can spread by blood transfusions.

Result: All blood donors were screened for five transmissible infections viz HIV, HBV, HCV, Malaria and Syphilis. Out of all voluntary blood donors 5 cases were seropositive cases, of which 2 were positive for HBV, 1 for HCV, 2 for Syphilis infection.

Conclusion: For a safe blood service in our country, where comprehensive laboratory tests are neither possible nor pragmatic, it is best to switch over to 100% voluntary donations, as it is now established that only voluntary non-remunerated regular donation is the safest. Thus, one of our key strategies to enhance blood safety is to focus on motivating non-remunerated blood donors and phasing out even replacement donors.

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How to Cite
Pooja, Swati Singh, & Mayurika Tyagi. (2022). Seroprevalence of Transfusion-Transmissible Infectious Agents (HIV, HBV, HCV, Syphilis, and Malaria) in Voluntary Blood Donors in a Tertiary Care Center in Ghaziabad (U.P.) . Journal of Coastal Life Medicine, 10(3), 20–24. Retrieved from


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