Study of Thyroid Disorder in Type 2 Diabetes Mellitus

Abstract

AIM: To study the prevalence of thyroid disorders in type2 diabetes mellitus.OBJECTIVES: 1. To classify types of thyroid dysfunction in type2 diabetes mellitus. 2. Evaluation of whether thyroid function tests were included in the investigational protocol of type 2 diabetes mellitus. 3. To assess the correlation between HbA1c and serum TSH. Materials and methods: 500 patients with type-2 diabetes, regardless of age or gender, were included in this cross-sectional study. Included were patients who had diabetes mellitus and solely primary thyroid impairment. Every participant followed a diabetic diet and received either insulin, oral anti-diabetic medications, or both. The blood sugars were tested by glucose uptake oxidase peroxidase, the chemiluminescence method used the thyroid function test (T3, T4, TSH), and Glycosylated hemoglobin was calculated by ion exchange high-performance liquid chromatography (HPLC). Results: In our study, patients with type 2 diabetes were much more likely to have thyroid impairment (34%). In the study group, there was a definite female preponderance; the prevalence was 64% among all diabetic patients. Between 50-59 years of age, most patients with diabetes come this age. 19.2% of the total study group patients were hypothyroidism which is the maximum, followed by 11.6% subclinical hypothyroidism. There is a female preponderance (22.8% of the total study group) among diabetic patients having thyroid disorders. Glycosylated hemoglobin and types of thyroid disorders are associated (p-value< .001).Conclusion:Current study shows a clear-cut female preponderance, with a 34% prevalence of overall thyroid disorder.