A Comparative Study to See the Effects of Perioperative Infusion of Lidocaine vs Dexmedetomidine on Hemodynamic Parameters in Patients Undergoing Laparoscopic Cholecystectomy Surgery
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Abstract
Background: Laparoscopic cholecystectomy is also found to be attributing to stress response and significant alteration of hemodynamics due to effects of pneumoperitoneum, patient’s position, and hypercapnia by absorption of CO2 as a result of pneumoperitoneum. It is also important to have good postoperative pain control for early recovery after laparoscopic cholecystectomy (LC). Intravenous lidocaine has anti-hyperalgesic, anti-inflammatory and analgesic effects while dexmedetomidine provides anti-nociception, analgesic, sedative and sympatholytic effects. Both these drugs can be used as adjuvants to improve recovery after LC.
Aim and Objective: To see the effects of perioperative infusion of Lidocaine vs dexmedetomidine on hemodynamic parameters during perioperative period in patients undergoing laparoscopic cholecystectomy surgery.
Methodology: The study, a non-randomized controlled trial conducted in a hospital setting, took place from 2019 to 2020 in the department of anesthesia at Santosh Medical College and Hospital in Ghaziabad, India. In this study, patients of either gender between the ages of 18yrs and 60yrs were scheduled for laparoscopic cholecystectomy. To perform a laparoscopic cholecystectomy, 70 adult patients of either sex who had ASA grades I or II were admitted. They were randomly split into two groups of 35 patients each.
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References
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