Study of Thyroid Dysfunction in Patients with Metabolic Syndrome

Abstract

Background: Thyroid impairment is common in patients with metabolic syndrome. The study's goal was to learn more about the interplay between tests for thyroid function and other markers of metabolic syndrome. Subject matter and method: According to the NCEP- ATP III diagnostic criteria for metabolic syndrome, 61 individuals with the condition were included in the research and divided into three groups. Thyroid tests were performed and compared to criteria for metabolic syndrome. The results showed that out of a total of 61 patients diagnosed with MetS, 24 (39.3 percent) were men, while 37 (60.7 percent) were female, for a ratio of men to women of 1:1.5. The average age of participants was 53.69 14.78 years old.  A majority of the patients belonged to the age group of ≥ 61 years. Of the 61 patients with MetS, 31 (50.8%) subjects had 3 components of MetS, 17 (27.9%) had 4 components of MetS and 13 (21.3%) had 5 components of MetS. The prevalence of metabolic syndrome in euthyroid, subclinical hypothyroid, hypothyroid, subclinical hyperthyroid and hyperthyroid patients was 67.2%, 9.8%, 13.1%, 6.6% and 3.3% respectively. The prevalence of thyroid dysfunction was 32.8%. Among 13 patients who had 5 components of MetS, only 5 (38.5%) patients were euthyroid and 8 (61.5%) had thyroid dysfunction. Conclusion: Overt hypothyroidism was the most frequent thyroid dysfunction observed in the present study. This study concludes that thyroid dysfunction increases as the number of metabolic syndrome components increases. Therefore, every patient with metabolic syndrome should be screened for thyroid function tests.