Antimicrobial Efficacy of Chitosan Nanoparticle Gel at the Implant Abutment Interface

Abstract

Purpose: To develop a chitosan based thermosensitive hydrogel for sealing and lubricating purposes in dental implant systems.

Materials and Methods:To check for the bacterial leakage at the IAI, a stained  implant is viewed under stereoelectronic microscope. Chitosan nanoparticle gel is prepared and placed around the implant abutment interface.The implants were placed in the Agar medium inoculated with streptococcus mutans and pseudomonas, incubated in an incubator for 120 hours at 37°C. For Anti-microbial analysis.

Results - There was no significant differences between two implant designs ( P > 0.05), but showing activity of 100% better than the control group (control showed no zone of inhibitions against bacteria).

Conclusions: Based on our findings, it could be concluded that the thermosensitive and antimicrobial hydrogel with sealing and lubricating ability was successfully prepared and it has shown anti-microbial efficiency against both Streptococcus mutans and Pseudomonas.