Pediatric Status Epilepticus Clinical Profile and Short-Term Results Prospective cohort study
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Abstract
Introduction: In order to avoid permanent brain damage and death, “Status Epilepticus (SE)” is a medical emergency that needs to be treated right away. The motive of this research was to describe the clinical characteristics and immediate results of pediatric SE patients.
Methods: A prospective cohort study involving patients with SE from 1 month to 18 years old was carried out in a tertiary care facility. Data from the clinical, laboratory, and demographic sources were gathered and examined.
Results: The mean age of the 65 subjects who were enrolled was 7.6 ±4.2 years, and 35 (53.8%) of them were men. The two most prevalent causes of SE were acute symptoms (52.3%) and fever (30.8%). Generalized convulsive seizures were the most common seizure type (80.0%), and their median duration was 60 minutes. 56 (86.2%) patients received intravenous benzodiazepines as the first line of treatment, while 35 (53.8%) patients received antiepileptic medications as the second line of treatment. Within 60 minutes of the start of treatment, 35 patients (53.8%) had completely recovered from SE. Respiratory depression (6.2%) and SE refractory to therapy (7.7%) were the two main consequences, and the mortality rate was 7.7%.
Conclusion: This prospective cohort study sheds light on pediatric SE's short-term prognoses and clinical features in tertiary care hospitals. The findings show that most people recover from SE within 60 minutes of beginning treatment. Second-line phenytoin may worsen SE severity and decrease SE resolution
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References
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