Streptozotocin-Induced Diabetic Retinopathy in Swiss Albino Mice: Anatomical, Behavioral, and Histopathological Evaluation of the Colostrum and Astaxanthin in the Retinas
Main Article Content
Insulin-secreting pancreatic beta cells are damaged and insulin receptors become resistant in people with diabetes mellitus, causing an increase in blood sugar. Changing dietary and exercise habits are the primary cause of diabetes mellitus's development. When left untreated, diabetes mellitus may cause a number of secondary problems that diminish quality of life over time. DR, DKN, DN, and DCM are the four most common secondary consequences of diabetes. Glycated proteins and AGE are formed when glucose interferes with proteins, which is a major cause of the aforementioned difficulties. Furthermore, AGE are known to produce cellular oxidative stress, inflammation, mitochondrial dysfunction, modification of ion channel states, and functional alterations of DNA & mRNA. In this publication, the effects of streptozotocin on the retinas of swiss albino mice are examined.
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