Subclinical Hypothyroidism: Biochemical and Molecular Cardiovascular Disease Risks
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This research aims to find biochemical and molecular indicators of subclinical hypothyroidism that may be used to diagnose cardiovascular disease at an early stage. To determine which biochemical and molecular indicators are most useful for the early diagnosis of cardiovascular disease in people with subclinical hypothyroidism, a case-control research design was used in the current investigation. Results suggest that the mean CBMN frequency was higher in men than in women, and that the mean MN frequency was higher in those with lower HDL-C.
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Biondi B, Cooper DS. The clinical significance of subclinical thyroid dysfunction. Endocr Rev. 2008 Feb;29(1):76-131.