A Study on Regulation of HDAC1 2 Activity by Ube3a Implication in Angelman Syndrome

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Published: Jan 11, 2023
Keywords:
Angelman Syndrome Regulation HDAC1 2 Ube3a

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Pavan Kumar Ediga
Neurosurgeon. Department of Neurosurgery, Krishna Institute of Medical Sciences, Krishna VishwaVidyapeeth “Deemed to Be University”, Karad – 415110, Maharashtra
Chinmay Vilas Phadtare
Neurosurgeon, Department of Neurosurgery, Krishna Institute of Medical Sciences, Krishna VishwaVidyapeeth “Deemed to Be University”, Karad – 415110, Maharashtra

Abstract

The purpose of this research is to learn how Ube3a affects HDAC activity in individuals with Angelman syndrome. Heterozygous Ube3a-deficient mice were bought from the lab and kept in the usual conditions with pelleted food and water. Sigma Stat was used for the statistical analysis. Our results show that Ube3a controls HDAC1 and HDAC2 transcription.

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How to Cite
Ediga, P. K. ., & Phadtare, C. V. . (2023). A Study on Regulation of HDAC1 2 Activity by Ube3a Implication in Angelman Syndrome. Journal of Coastal Life Medicine, 11(1), 2897–2903. Retrieved from https://www.jclmm.com/index.php/journal/article/view/773
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Vol. 11: Number 1, 2023
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Articles

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