Host Modulation Therapy with Short Term Use of Oral Omega-3 Fatty Acids as an Adjunct to Non-Surgical Periodontal Therapy – A Pilot Project
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Abstract
Introduction A fairly popular beneficial therapy for the non-surgical administration of periodontal infection is host modulation therapy (HMT). A commonly administered agent, Omega-3 fatty acids, otherwise called PUFA, has shown promising results of the various modalities explored in the recent years. This objective of this study was to assess its clinical impact on periodontal markers in individuals with periodontitis. Methods: For this three-month preliminary trial, scaling and root planing were performed on 60 patients with periodontitis who were between the ages of 18 and 70. From that point onward, they were randomly assigned into two groups, each with 30 patients: the experimental group, which got omega - 3 fatty acid gel capsules for a period of 2 weeks, and the control group, which got no further therapy. The clinical parameters assessed at baseline, one month, and 90 days post-introductory treatment were periodontal charting which included probing depths and clinical attachment loss; plaque index and bleeding score. Results: Despite the fact that the clinical periodontal parameters, in both the test and control groups fundamentally improved over the long run (P < 0.001), there were no huge contrasts between the 2 groups when compared with each other in any of the time intervals (P > 0.05) except for probing depths and clinical attachment levels. (P< 0.001). Furthermore, the experimental group's mean score contrasts were only a somewhat higher than those of the control group. Conclusion: Within the limitations of the study, Omega-3 fatty acids as a host modulation agent might demonstrate to be an economical and practical adjunct to non-surgical periodontal therapy in the treatment of patients with periodontitis.
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