Multiparametric Magnetic Resonance Imaging in Evaluation of Benign and Malignant Breast Masses with Pathological Correlation

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Published: May 28, 2023
Keywords:
Breast neoplasms Magnetic resonance imaging Diagnostic accuracy Pathological correlation Multiparametric imaging

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Anand Guddur
Department of Oncology, Krishna Institute of Medical Sciences, Krishna Vishwa Vidyapeeth, "Deemed To Be University", Karad , Malkapur, Karad (Dist. Satara), Maharashtra, India. PIN – 415539"
Atul Bhanudas Hulwan
Assistant Professor, Department of PATHOLOGY, Krishna Institute of Medical Sciences, Krishna Vishwa Vidyapeeth, ""Deemed to Be University", Karad, Malkapur, Karad (Dist. Satara), Maharashtra, India. PIN – 415539
Amol Bhoite
Assistant Professor, Department of RADIO-DIAGNOSIS, Krishna Institute of Medical Sciences, Krishna Vishwa Vidyapeeth, ""Deemed to Be University", Karad Malkapur, Karad (Dist. Satara), Maharashtra, India. PIN – 415539"

Abstract

Objective: In a cohort of 45 patients, this study sought to evaluate the diagnostic efficacy of multiparametric magnetic resonance imaging (MRI) in discriminating benign from malignant breast masses with pathological association.


Methods: For this prospective investigation, 45 female patients with suspect breast tumors were enrolled. All patients had multiparametric MRI scans, including diffusion-weighted, dynamic contrast-enhanced, T1-weighted, and T2-weighted scans. All patients had a biopsy or a surgical excision after an MRI to check for pathological association. Each imaging parameter's diagnostic performance metrics, such as sensitivity, specificity, and accuracy, as well as the combined multiparametric MRI findings, were calculated.


Results: The individual MRI parameters and the overall multiparametric MRI findings' sensitivity, specificity, accuracy, PPV, and NPV were computed. The findings showed that the best diagnostic accuracy for distinguishing between benign and malignant breast masses was achieved by combining dynamic contrast-enhanced MRI with T2-weighted imaging.


Conclusion: When assessing benign and malignant breast masses, multiparametric MRI, particularly the union of T2-weighted imaging and dynamic contrast-enhanced MRI, shown promising diagnostic accuracy. These results imply that multiparametric MRI may be a useful tool in clinical practice for increasing the precision of the diagnosis of breast cancer, hence assisting in the planning of the patient's care and treatment.

Article Details

How to Cite
Guddur, A., Hulwan, A. B. ., & Bhoite, A. (2023). Multiparametric Magnetic Resonance Imaging in Evaluation of Benign and Malignant Breast Masses with Pathological Correlation. Journal of Coastal Life Medicine, 11(1), 3286–3295. Retrieved from https://www.jclmm.com/index.php/journal/article/view/890
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Vol. 11: Number 1, 2023
Section
Articles

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