Role of Insulin Resistance in Patients with Acne Vulgaris and Hirsutism in North India: A Cross-Sectional Study

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Neha Deokar
Mohan Kale
Gauri Bhale


Objective: This cross-sectional study's goal was to find out whether patients from North India had an increased risk of insulin resistance, acne vulgaris, or hirsutism.

Methods: For this study, a total of 200 patients presenting with hirsutism and acne vulgaris were enrolled. Clinical information was gathered, including medical history, BMI, fasting blood glucose, insulin levels, and HOMA-IR (homeostatic model assessment of insulin resistance) scores. Using defined grading standards, the severity of hirsutism and acne vulgaris was evaluated. To ascertain the relationship between insulin resistance and the occurrence of hirsutism and acne vulgaris, statistical studies were carried out.

Results: The presence and severity of acne vulgaris and hirsutism were significantly positively correlated with insulin resistance, as indicated by increased HOMA-IR values. Furthermore, compared to patients with milder versions of the illnesses, those with severe hirsutism and acne vulgaris had higher rates of insulin resistance. In addition, patients with insulin resistance, concurrent acne vulgaris, and hirsutism were shown to have higher BMI and fasting blood glucose levels.

Conclusion: In conclusion, our research supports the notion that insulin resistance contributes to the development of hirsutism and acne vulgaris in North Indian patients. These results highlight how crucial it is to take insulin resistance into account as a potential contributing factor when treating acne vulgaris and hirsutism in clinical practice. It is necessary to conduct more research to examine specialized treatment plans for people with insulin resistance and related dermatological symptoms.

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Deokar, N. ., Kale, M. ., & Bhale, G. . (2023). Role of Insulin Resistance in Patients with Acne Vulgaris and Hirsutism in North India: A Cross-Sectional Study. Journal of Coastal Life Medicine, 11(2), 73–76. Retrieved from


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