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Aim: The purpose of the current study was to assess whether cold saline irrigation as the final irrigant reduced postoperative pain in teeth with symptomatic irreversible pulpitis treated in a single visit. Material and method: In present study 60 patients were selected which were further randomly divided into two equal groups. After finishing the biomechanical preparation, the final irrigation in the cold saline group employed 2.5°C saline solution for 5 minutes, whereas in the control group (normal saline), the same solution held at the root temperature was used. In the current investigation, a single visit was used as the treatment. Using a visual analogue scale, participants were asked to rate the severity of their postoperative discomfort. Result: Statistically, significant difference was observed in VAS score between both groups at 6 hours. Conclusion: The outcome demonstrates that a single visit root canal treatment can effectively be followed by cold saline irrigation to lessen post-operative pain.
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